日々のつれづれ

不惑をむかえ戸惑いを隠せない男性の独り言

USがPSA検査の対象年齢を見直し

PSA screening test is used to diagnose the prostate cancer in US.
On the other hand, Japan doesn't recognize the PSA test as the effective test because of a poor evidence.
I wrote this topic in the previous diary.

Today, U.S. Preventive Services Task Force rethink the effectiveness of this test.
Previously, this test is thought to be useful over 75-years-old male, but this statement shows that this would be useful for almost all male.

These points are

  • The magnitude of harms from screening (e.g., falsely high PSA levels, psychological effects, unnecessary biopsies, overdiagnosis of indolent tumors) is "at least small."
  • The magnitude of treatment-associated harms (i.e., adverse effects of surgery, radiation, and hormonal therapy) is "at least moderate" ― particularly because of overtreatment among men with low-grade disease.
  • The 10-year mortality benefit of PSA-based prostate cancer screening is "small to none."
  • The overall balance of benefits and harms results in "moderate certainty that PSA-based screening ... has no net benefit."
http://general-medicine.jwatch.org/cgi/content/full/2011/1027/1

I think that the MHLW (Ministry of Health, Labour and Welfare), that is Japanese FDA, should discuss more. The time has come, haven't it?