In this ASCO, T-DM1 which is that DM1 is connected with trastzumab (Herceptin) showed the good result in clinical trial. T-DM1 is usually called as trastuzumab emtansine.In this trial, T-DM1 was treated to the HER2 positive breast cancer p…

Sorafenib which is known as Nexavar is pan-RTK inhibitor and molecular targeted drug. This is developed by Bayer and Onyx Pharmaceuticals, and FDA has approved it to treat hepatocellular carcinoma and renal carcinoma. In Japan, this drug h…

久々にRのことを書こうと思います。 つい最近、read.tableのことで質問があり、こんな疑問もあるなあ、と思ったのがきっかけなのデスが。read.table関数はread.XXX(read.delim, read.csv, read.csv2)系のベースになっている関数で、タブ区切り、CSVでない形…

Pertuzumab is the next-generation molecular targeted drug and cure the HER2-positive breast cancer to inhibit the dimerization of HER2 receptors.Today, pertuzumab was approved by FDA and it can be used to treatment HER2-positive breast can…

At ASCO 2012, it was shown that Gemcitabine might not improve the prognosis of the HER2-negative and lymph node positive breast cancer patients.For the adjuvant chemotherapy to the HER2-negative and lymph node positive breast cancer patien…

Now we can use several adjuvant chemotherapy for the breast cancer treatment after surgery, but it is not clear which is the best. Because each patient have different background and the breast cancer is classified to several subtype, to ha…

久しぶりに英語を勉強した。depend(s) on ... と depending on ... どっちも同じ意味と思っているけど、使い方が分からない。 dependは「...に頼る」という動詞なので、depending on ... は現在進行形になっている。つまり、こういうこと理解した。 depend(s…

The diagnosis for baby's genetic mutation has improved.The researchers succeeded to detect the Down's syndrome using the mother blood and father saliva.It is well-known that non cellular DNA is floating into the pregnant women's blood. Pre…

Usually, we use the "risk" to explain the possibility to become illness.However, I suppose that it is difficult for almost all the people to understand the meaning of risk.For example, one patient have the symptom of cancer and the doctor …

I'm thinking that many people overfocus to improve the performance and they don't pay attention to the meaning of this results or algorithm.This is very awful situation, because the aim of algorithm making is that we understand the system …

BBC said that the awareness of cannabis smoking.The cannabis is illegal drug in Japan, but other countries is not. Although I don't know the thinking of cannabis in UK, maybe several people are thinking that smoking cannabis is one of recr…

Recent BBC news indicated two controversial topics.One is that Iron tablet is useful for women anemia, Iron pills may help women beat fatigue Prescribing iron supplements may help some women with fatigue even if they are not officially ana…

BBC reported that the premature birth are linking to mental health.According to the research at King's College London and the Karolinska Institute in Sweden, bipolar disorder, depression and psychosis might be linked to premature birth.How…

今週のお題「おすすめのレストラン」去年、私は結婚10周年でした。 思えば、結婚してから急に仕事が忙しくなり、単身赴任と転勤を繰り返す日々で何だかよく分からないまま時間が過ぎていった･･･幸いにも二人の子供に恵まれ、健康に毎日を過ごせている。 これ…

Today's topic in BBC is that the rat injured leg recovered this waking ability because of reconnecting to the spinal cord.This is published in Science journal. The researchers injured the rat leg by the chemical and these rats lost the abi…